a) Either L-lactic acid or DL-lactic acid is just one
of the forms that the lactic acid exists. Under the general
condition, both are of the same physical and chemical property,
and they are of different physiological effects to the human
body for the opposite direction of optical rotation.
b) Proceeding from the method of production, for example,
when the fermentation is adopted, the different bacteria
and fermenting conditions will produce the optical isomers
of L-lactic acid, D-lactic acid and a certain proportion
of mixed DL-lactic acid. The synthesis may obtain the racemic
DL-lactic acid only, where the two optical isomers of D
and L account for 50% respectively, nearly zero at the optical
rotation.
c) Proceeding from the application, for example in the
food additive industry, L-lactic acid is easier to be absorbed
in the human body and may directly enter into the internal
metabolism without presence of acidosis, because the human
muscle tissue itself contains the L-lactate dehydrogenase
available for digestion of L-lactic acid. In such a case,
the WHO proposes to restrict the addition of D or DL-lactic
acid into the food for infant and pre-school children, but
not to restrict the L-lactic acid. However, the L-lactic
acid from fermentation shows too much difference in quality
due to the application of different technique. Particularly,
the product low at purity is unstable in quality and contains
more impurities harmful to the human body. On the contrary,
the product from synthesis is pure white in color, good
at thermal stability and easier to control in quality; it
has been extensively used in synthetical solvent.
d) So, we won't simply say which one is better among L-lactic
acid, DL-lactic acid, fermented lactic acid and synthetic
lactic acid. The proper judgment must be made only with
reference to the specific field of application and product
quality. However, the high quality L-lactic acid from JMB,
except the pure natural lactic acid produced by means of
fermentation, still features the two major properties of
higher optical purity and higher purity, which has combined
the advantages of fermentation and synthesis and is suitable
to apply in every field. |